Journal
CURRENT OPINION IN CHEMICAL BIOLOGY
Volume 19, Issue -, Pages 99-106Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.cbpa.2014.01.018
Keywords
-
Categories
Ask authors/readers for more resources
Herein, we highlight a selection of recent successes in the creation of artificial metalloenzymes. A particular emphasis is set on different anchoring methods to incorporate the abiotic metal cofactor within the host protein as well as promising strategies for the de novo design of artificial metalloenzymes. Both approaches yield promiscuous catalytic activities which expand the catalytic repertoire of biocatalysis and synthetic biology. Moreover, we summarize laboratory evolution protocols which have contributed to unravel the full potential of artificial metalloenzymes.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available