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Improving carbon fixation pathways

Journal

CURRENT OPINION IN CHEMICAL BIOLOGY
Volume 16, Issue 3-4, Pages 337-344

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.cbpa.2012.05.002

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Funding

  1. National Institute of General Medical Sciences [F32GM093516]
  2. Army Research Office [W911NF-09-1-0226]
  3. DOE ARPA-E [DE-0000079]
  4. Wyss Institute for Biologically Inspired Engineering

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A recent resurgence in basic and applied research on photosynthesis has been driven in part by recognition that fulfilling future food and energy requirements will necessitate improvements in crop carbon-fixation efficiencies. Photosynthesis in traditional terrestrial crops is being reexamined in light of molecular strategies employed by photosynthetic microbes to enhance the activity of the Calvin cycle. Synthetic biology is well-situated to provide original approaches for compartmentalizing and enhancing photosynthetic reactions in a species independent manner. Furthermore, the elucidation of alternative carbon-fixation routes distinct from the Calvin cycle raises possibilities that novel pathways and organisms can be utilized to fix atmospheric carbon dioxide into useful materials.

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