Journal
CURRENT OPINION IN CELL BIOLOGY
Volume 25, Issue 1, Pages 99-106Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2012.08.015
Keywords
-
Categories
Funding
- Public Health Service [GM071049]
- National Institute of General Medicine
Ask authors/readers for more resources
mRNA localization is a crucial mechanism for post-transcriptional control of gene expression used in numerous cellular contexts to generate asymmetric enrichment of an encoded protein. This process has emerged as a fundamental regulatory mechanism that operates in a wide range of organisms to control an array of cellular processes. Recently, significant advances have been made in our understanding of the mechanisms that regulate several steps in the mRNA localization pathway. Here we discuss the progress made in understanding localization element recognition, paying particular attention to the role of RNA structure. We also consider the function of mRNP granules in mRNA transport, as well as new results pointing to roles for the endocytic pathway in mRNA localization.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available