Journal
CURRENT OPINION IN CELL BIOLOGY
Volume 22, Issue 3, Pages 357-364Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2010.03.003
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Funding
- National Cancer Institute [CA04382]
- State of Connecticut
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Long non-coding RNAs (IncRNAs) are mRNA-like, non-protein-coding RNAs that are pervasively transcribed throughout eukaryotic genomes. Rather than silently accumulating in the nucleus, many of these are now known or suspected to play important roles in nuclear architecture or in the regulation of gene expression. In this review, we highlight some recent progress in how IncRNAs regulate these important nuclear processes at the molecular level.
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