4.5 Article

Who gets cut during cell death?

Journal

CURRENT OPINION IN CELL BIOLOGY
Volume 22, Issue 6, Pages 859-864

Publisher

CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2010.08.021

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Funding

  1. Fund for Scientific Research-Flanders (Belgium) [G.0048.08]
  2. Ghent University [BOF07/GOA/012]
  3. Interuniversity Attraction Poles [IUAP06]

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The recent introduction of positional proteomics made it possible to screen for protease processing events on a proteome-wide scale. As a highly regulated and protease-dependent process, cell death has been particularly well-studied with these emerging technologies. This review provides an overview of the results obtained at the exciting interface between proteomics, protease biology and cell death.

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