Journal
CURRENT OPINION IN CELL BIOLOGY
Volume 21, Issue 5, Pages 717-723Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2009.07.001
Keywords
-
Categories
Ask authors/readers for more resources
Fat is an extremely large atypical cadherin involved in the regulation of cell adhesion, tissue growth, and planar cell polarity (PCP). Recent studies have begun to illuminate the mechanisms by which Fat performs these functions during development. Fat relays signals to the Hippo pathway to regulate tissue growth, and to PCP proteins to regulate tissue patterning. In this review we briefly cover the historical data demonstrating that Fat regulates tissue growth and tissue patterning, and then focus on advances in the past three years illuminating the mechanisms by which Fat controls growth and planar polarity in flies and mammals.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available