Journal
CURRENT OPINION IN CELL BIOLOGY
Volume 21, Issue 1, Pages 51-58Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2009.01.004
Keywords
-
Categories
Funding
- National Institute of Health [R01 GM075249]
- Rockefeller University
- Charles H Revson Biomedical Fellowship
Ask authors/readers for more resources
The directed movement of chromosomes during mitosis and meiosis relies on microtubule-mediated connections between spindle poles and kinetochores assembled on chromosomes. The molecular basis for the dynamic interaction between microtubules and kinetochores is just beginning to be unveiled. Here, focusing on the mitotic centromere kinase Aurora B, we review our current understanding of the signaling pathways that correct erroneous microtubule attachment at kinetochores. We evaluate several potential models that may explain how maloriented attachments are recognized and processed by the Aurora B pathway.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available