Journal
CURRENT OPINION IN BIOTECHNOLOGY
Volume 25, Issue -, Pages 1-7Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2013.08.005
Keywords
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Funding
- Commission of the European Community through INsPiRE [284460]
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Nature comprises an untapped pool of unique compounds with high structural uniqueness and exceptional properties. At the core of natural products (NPs) discovery is the identification procedure and NMR remains the most efficient method. Technical improvements such as miniaturized and crycogenic NMR probes along with hyphenation capabilities and computational support are at the center of evolution. Concepts such as dereplication and metabolomics are increasingly adopted in NPs using the power of databases, currently fragmented. The introduction and utilization of these technical and computational implements could lead NPs research to more comprehensive structure identification and new holistic perspectives.
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