Journal
CURRENT OPINION IN BIOTECHNOLOGY
Volume 22, Issue 6, Pages 901-908Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2011.04.020
Keywords
-
Funding
- NIH [R00 EB009105, P30 EB011317]
Ask authors/readers for more resources
Several nanoparticle platforms are currently being developed for applications in medicine, including both synthetic materials and naturally occurring bionanomaterials such as viral nanoparticles (VNPs) and their genome-free counterparts, virus-like particles (VLPs). A broad range of genetic and chemical engineering methods have been established that allow VNP/VLP formulations to carry large payloads of imaging reagents or drugs. Furthermore, targeted VNPs and VLPs can be generated by including peptide ligands on the particle surface. In this article, we highlight state-of-the-art virus engineering principles and discuss recent advances that bring potential biomedical applications a step closer. Viral nanotechnology has now come of age and it will not be long before these formulations assume a prominent role in the clinic.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available