Journal
CURRENT OPINION IN BIOTECHNOLOGY
Volume 22, Issue 6, Pages 775-783Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2011.04.024
Keywords
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Funding
- Synthetic Biology Engineering Research Center
- National Science Foundation [0540879]
- Joint BioEnergy Institute
- U.S. Department of Energy, Office of Science, Office of Biological and Environmental Research [DE-AC02-05CH11231]
- Natural Sciences and Engineering Research Council of Canada
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Production of biofuels from renewable resources such as cellulosic biomass provides a source of liquid transportation fuel to replace petroleum-based fuels. This endeavor requires the conversion of cellulosic biomass into simple sugars, and the conversion of simple sugars into biofuels. Recently, microorganisms have been engineered to convert simple sugars into several types of biofuels, such as alcohols, fatty acid alkyl esters, alkanes, and terpenes, with high titers and yields. Here, we review recently engineered biosynthetic pathways from the well-characterized microorganisms Escherichia coli and Saccharomyces cerevisiae for the production of several advanced biofuels.
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