Journal
CURRENT OPINION IN BIOTECHNOLOGY
Volume 19, Issue 5, Pages 437-444Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.copbio.2008.07.012
Keywords
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Funding
- National Science Foundation [BES0422791, BES0329482]
- Environmental Protection Agency [R833008]
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Given the immense risk posed by widespread environmental pollution by inorganic and organic chemicals, novel methods of decontamination and clean-up are required. Owing to the relatively high cost and the non-specificity of conventional techniques, bioremediation is a promising alternative technology for pollutant clean-up. Advances in bioremediation harness molecular, genetic, microbiology, and protein engineering tools and rely on identification of novel metal-sequestering peptides, rational and irrational pathway engineering, and enzyme design. Recent advances have been made for enhanced inorganic chemical remediation and organic chemical degradation using various pathway-engineering approaches and these are discussed in this review.
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