Journal
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS
Volume 13, Issue 12, Pages -Publisher
SPRINGER
DOI: 10.1007/s11910-013-0409-5
Keywords
Depression; Parkinson's disease; Mood disorder; Psychiatric; Antidepressant; Cognitive behavioral therapy; Electroconvulsive therapy; Quality of life; Treatment; Suicide; Major depression: dysthymia; Minor depression; Subsyndromal depression; Epidemiology; Pathophysiology
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Funding
- NCATS NIH HHS [U54 TR001456] Funding Source: Medline
- NINDS NIH HHS [U54 NS065701] Funding Source: Medline
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Depressive disturbances are common in patients with Parkinson's disease (PD) and influence many other clinical aspects of the disease. In addition to causing inherent emotional distress, depressive disorders negatively impact quality of life, motor and cognitive deficits, functional disability, and other psychiatric comorbidities in patients with PD. Knowledge of the pathophysiology of PD depression remains limited. However, clinical studies demonstrate the efficacy of medications and psychotherapies for PD depression, underscoring the importance of their timely detection and concerted management.
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