Journal
CURRENT MEDICINAL CHEMISTRY
Volume 18, Issue 14, Pages 2045-2059Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/092986711795656225
Keywords
Fullerenes; radical scavengers; drug carriers; photodynamic therapy; endofullerenes; MRI contrast agents
Funding
- NSF [CBET-0967423]
- Susan G. Komen
- Directorate For Engineering
- Div Of Chem, Bioeng, Env, & Transp Sys [0967423] Funding Source: National Science Foundation
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Fullerenes as a unique class of carbon allotropes have been studied extensively for their distinctive material properties and potential technological applications, including those in biology and medicine. Since a major focus in the latter has been on drug development and formulation, in this paper we highlight some representative studies related to such a focus, including the use of fullerenes for drug-like functions and for their improving the formulation of established drugs. Also discussed are some other potential medically relevant applications of fullerenes, such as their serving as potent agents in photodynamic therapy and magnetic imaging.
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