4.6 Review

Syntheses, Transformations and Pharmaceutical Applications of Kynurenic Acid Derivatives

Journal

CURRENT MEDICINAL CHEMISTRY
Volume 16, Issue 36, Pages 4828-4842

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/092986709789909602

Keywords

Kynurenic acid; kynurenic acid derivatives; neurological disorders; schizophrenia; retinal damage; diabetes mellitus; hypertension

Funding

  1. [ETT-215/2006]
  2. [NKTH 08/2004]
  3. [OTKA K75628]

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The syntheses and transformations of 4-hydroxyquinoline-2-carboxylic acid, kynurenic acid, are reviewed, and special attention is paid to the pharmacological activities and pharmaceutical applications of its derivatives.

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