Quantitative Analysis of Optical Coherence Tomography Angiography Features in Patients with Nonocular Behcet's Disease

Purpose: To quantitatively measure the flow, nonflow, density, and foveal avascular zone (FAZ) assessment tool parameters of optical coherence tomography angiography (OCTA) in patients with nonocular Behcet's Disease (BD), and to compare the results with those obtained in healthy controls. Methods: FAZ parameters, flow area of choriocapillaris, and vessel density values of both superficial (SCP) and deep capillary plexuses (DCP) were measured using OCTA. Results: The FAZ area in SCP, FAZ area in full retinal vasculature, and FAZ perimeter were significantly higher and foveal density-300 was significantly lower in the BD group than in the control group (p = 0.008, p = 0.015, p = 0.011, and p = 0.045, respectively). Vessel density of the foveal region in SCP and DCP were significantly lower in the BD group than in the control group (p = 0.039 and p = 0.010). Conclusion: Lower capillary vessel densities, particularly in the foveal region, could be considered a subclinical form of ocular involvement in nonocular BD.