Journal
CURRENT DRUG METABOLISM
Volume 13, Issue 4, Pages 440-446Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138920012800166517
Keywords
Liposomes; micelles; nanoparticles; PLGA; SLN; nanotoxicity
Funding
- National Natural Science Foundation of China [30801304, 81071273, 31170929]
- Foundation for the Author of National Excellent Doctoral Dissertation of P. R. China (FANEDD) [200977]
- Program for New Century Excellent Talents in University [NCET-08-0373]
- Funding for Distinguished Young Scientists in Sichuan [2010JQ0066]
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Nowadays, biodegradable nanoscale preparations such as liposomes, micelles, nanoparticles (NPs), and solid lipid nanoparticles (SLN) have attracted increasing attention from major researchers. Meanwhile the biosafety of the nanomaterials brings more and more attention. Toxicity of the biodegradable nanoscle preparations varies depending on their particle size, shape, surface structure, et al. This article aims to review the toxicity of the above-mentioned nanoscale preparations and the relative methodology. It may be significant for successful use of more nanoscale preparations in clinical practice
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