Journal
CURRENT BIOLOGY
Volume 23, Issue 20, Pages R923-R925Publisher
CELL PRESS
DOI: 10.1016/j.cub.2013.09.030
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Chromosome segregation requires the removal of cohesion and catenation between sister chromosomes, two physical linkages established during DNA replication. Two new studies reveal that, among other functions, the wings apart-like protein (Wapl) coordinates cohesin removal with decatenation of sister chromosomes during mitosis in mammalian cells.
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