Journal
CURRENT BIOLOGY
Volume 20, Issue 17, Pages R780-R785Publisher
CELL PRESS
DOI: 10.1016/j.cub.2010.07.007
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Cytosine methylation is an ancient process with conserved enzymology but diverse biological functions that include defense against transposable elements and regulation of gene expression. Here we will discuss the evolution and biological significance of eukaryotic DNA methylation, the likely drivers of that evolution, and major remaining mysteries.
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