Journal
CURRENT BIOLOGY
Volume 19, Issue 17, Pages R790-R799Publisher
CELL PRESS
DOI: 10.1016/j.cub.2009.07.029
Keywords
-
Categories
Funding
- Polish Ministry of Science and Higher Education
- Max-Planck-Society
- German Research Foundation (DFG)
- European Commission
Ask authors/readers for more resources
Together with cell growth, division and death, changes in cell shape are of central importance for tissue morphogenesis during development. Cell shape is the product of a cell's material and active properties balanced by external forces. Control of cell shape, therefore, relies on both tight regulation of intracellular mechanics and the cell's physical interaction with its environment. In this review, we first discuss the biological and physical mechanisms of cell shape control. We next examine a number of develop mental processes in which cell shape change - either individually or in a coordinated manner - drives embryonic morphogenesis and discuss how cell shape is controlled in these processes. Finally, we emphasize that cell shape control during tissue morphogenesis can only be fully understood by using a combination of cellular, molecular, developmental and biophysical approaches.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available