Journal
CURRENT BIOLOGY
Volume 18, Issue 10, Pages R420-R423Publisher
CELL PRESS
DOI: 10.1016/j.cub.2008.04.014
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The Arp2/3 complex is a powerful nucleator of actin filaments when activated. A recent study has now revealed that this complex is not only subject to positive control but that there also exists a brake on its activity. This brake can suppress both the basal activity of the Arp2/3 complex as well as its activation by nucleation-promoting factors.
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