4.6 Article

In Vitro Experimental Investigation of Voice Production

Journal

CURRENT BIOINFORMATICS
Volume 6, Issue 3, Pages 305-322

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/157489311796904637

Keywords

Artificial vocal folds; flow-induced acoustics; fluid-structure-acoustic interaction; glottal fluid flow; human phonation; structural dynamics; voice

Funding

  1. German Research Foundation (DFG) [FOR 894/1]
  2. Graduate School of Advanced Optical Technologies of the University Erlangen-Nuremberg (SAOT)
  3. U.S. National Institute on Deafness and Other Communication Disorders (NIDCD) [R01DC009616, R01DC005788]

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The process of human phonation involves a complex interaction between the physical domains of structural dynamics, fluid flow, and acoustic sound production and radiation. Given the high degree of nonlinearity of these processes, even small anatomical or physiological disturbances can significantly affect the voice signal. In the worst cases, patients can lose their voice and hence the normal mode of speech communication. To improve medical therapies and surgical techniques it is very important to understand better the physics of the human phonation process. Due to the limited experimental access to the human larynx, alternative strategies, including artificial vocal folds, have been developed. The following review gives an overview of experimental investigations of artificial vocal folds within the last 30 years. The models are sorted into three groups: static models, externally driven models, and self-oscillating models. The focus is on the different models of the human vocal folds and on the ways in which they have been applied.

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