Journal
CURRENT ALLERGY AND ASTHMA REPORTS
Volume 13, Issue 4, Pages 347-353Publisher
CURRENT MEDICINE GROUP
DOI: 10.1007/s11882-013-0352-1
Keywords
Celiac; Celiac disease; Autoimmune; Addison's disease; Addison's; Type 1 diabetes; Autoimmune thyroiditis; Hashimoto's thyroiditis; Graves disease; Cryptogenic hepatitis; Celiac hepatitis; Primary biliary cirrhosis; Sjogren's syndrome; Systemic lupus erythematous; SLE; Lupus; Antiphospholipid syndrome; Psoriasis; Vitiligo; Alopecia acreta; Dermatitis herpetiformis
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Celiac disease (CD) is an autoimmune condition affecting the small intestine, triggered by the ingestion of gluten, the protein fraction of wheat, barley, and rye. There is a strong linkage between CD and HLA-DQ2 and HLA-DQ8 haplotypes. Multiple case reports and small series suggest concordance between CD and other autoimmune disorders. This paper provides a brief overview of the pathogenesis of CD and reviews the literature regarding associations between CD and other autoimmune diseases, including the potential effects of gluten-free diet therapy on the prevention or amelioration of associated diseases.
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