Journal
CRYSTENGCOMM
Volume 20, Issue 35, Pages 5112-5118Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8ce01106k
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Funding
- National Natural Science Foundation of China [21673279]
- Youth Innovation Promotion Association of CAS [2012242]
- China Postdoctoral Science Foundation [2017LH045]
- CAS [2017LH045]
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Carboxylate moieties are less considered in the field of pharmaceutical cocrystal research, although they are contained in some important drug substances and cocrystal formers. Here, we demonstrated that an amine-carboxylate intermolecular interaction (N-H-OOC) can be used as a supramolecular synthon for pharmaceutical cocrystal design.
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