Fabrication of CuO nanowalls on Cu substrate for a high performance enzyme-free glucose sensor

Enzyme-free determination of glucose on an ordered CuO nanowall-based Cu substrate modified electrode is investigated. The structure and morphology of the CuO nanowalls were characterized by X-ray diffraction and scanning electron microscopy. The growth mechanism of the sample and the influence factor of the preparation process are discussed. The electrochemical study has shown that the CuO nanowalls exhibit a higher catalytic effect on the glucose than the CuO nanosphere without Cu substrate. This may be attributed to the special structure of the nanomaterials and the substrate of the electronic conductive Cu. The amperometric response showed that the CuO nanowall-modified glassy carbon electrode has a good response for glucose with a linear range of 0.05 mu M to 10 mu M with a sensitivity of 0.5563 mu A mu M-1 in pH 9.2 phosphate buffered solutions.