Journal
CRYSTENGCOMM
Volume 11, Issue 9, Pages 1823-1827Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b904616j
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Funding
- Institute of Chemical and Engineering Sciences of A*STAR (Agency for Science, Technology and Research), Singapore
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The first example of a trimorphic cocrystal involving two active pharmaceutical ingredients (APIs), ethenzamide and gentisic acid, is reported; metastable polymorphs convert to the stable form upon solid-state grinding; pharmaceutical cocrystals involving two or more APIs have potential relevance to combination drugs.
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