Journal
CRYSTENGCOMM
Volume 10, Issue 7, Pages 856-864Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b715396a
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Four different screening techniques were used to form cocrystals of carbamazepine containing pharmaceutically acceptable carboxylic acids. Twenty-seven unique solid phases utilizing eighteen carboxylic acid coformers were generated in the screening experiments. Cocrystal formation and stability in water is reported. Phase solubility diagrams and triangular phase diagrams are used to illustrate how saturation of the reactants leads to supersaturation of the cocrystal.
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