4.0 Article

Crystal structures of 1-aryl-4-(biarylmethylene)piperazines, structurally related to adoprazine

Journal

CRYSTALLOGRAPHY REPORTS
Volume 59, Issue 7, Pages 1057-1062

Publisher

MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S1063774514080094

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Funding

  1. National Plan for Science, Technology, and Innovation (NSTIP) project [11-BIO2138-04]

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8-(4-((5-(4-Fluorophenyl)pyridin-3-yl)methyl)piperazin-1-yl)-3,4-dihydroquinolin-2(1H)-one hydrochloride (I) and 8-(4-([1,1'-biphenyl]-4-ylmethyl)piperazin-1-yl)-2-methoxyquinoline (II) were prepared in the crystalline state and studied by X-ray diffraction. The crystal packing drawing of compound (I) indicated extensive hydrogen bonding whereas in case of compound (II) showing C-Ha <-O short contact resulting in the formation of one-dimensional network.

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