Journal
CRYSTAL GROWTH & DESIGN
Volume 11, Issue 5, Pages 1777-1785Publisher
AMER CHEMICAL SOC
DOI: 10.1021/cg1017104
Keywords
-
Funding
- Australian Research Council (ARC) [DP0666961]
- CSIRO
- Australian Research Council [DP0666961] Funding Source: Australian Research Council
Ask authors/readers for more resources
Protic ionic liquids (PILs) have been evaluated as additives in protein crystalization trials. Ten ionic liquids were incorporated as additives along with the JCSG+ sparse matrix screen for the crystallization of lysozyme, glucose isomerase, and trypsin. When used as additives, the PILs were identified to influence the crystallization of these globular proteins. Crystal structures obtained for lysozyme with each of the 10 PILs under identical conditions showed no change in the crystal structure of the protein; however, in three of the ten cases fragments of the ionic liquids were observed to be incorporated within the protein.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available