Journal
JOURNAL OF NATURAL PRODUCTS
Volume 78, Issue 2, Pages 306-310Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np500586r
Keywords
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Funding
- National Natural Science Foundation of China [21372208, 41176120]
- NSFC-Shandong Joint Fund [U1406402]
- National High Technology Research and Development Program of China [2013AA092901]
- Program for New Century Excellent Talents in University [NCET-12-0499]
- State Key Laboratory of Bio-organic and Natural Products Chemistry [SKLBNPC12331]
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Three new citrinin analogues, penicitols A-C (1-3), and one new xanthone derivative, penixanacid A (4), together with four known biogenetically related compounds (5-8), were discovered from the extract of a mangrove-derived fungus, Penicillium chrysogenum HND11-24. The structures of penicitols A-C and penixanacid A were established through analysis of extensive spectroscopic data. Their cytotoxic activity against HeLa, BEL-7402, HEK-293, HCT-116, and A549 cell lines was evaluated.
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