Journal
JOURNAL OF NATURAL PRODUCTS
Volume 78, Issue 11, Pages 2827-2831Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.jnatprod.5b00540
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Funding
- Japan Society for Promotion of Science [24380050]
- Grants-in-Aid for Scientific Research [15H04480] Funding Source: KAKEN
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Nonfilamentous actinobacteria have been less studied as secondary metabolite producers than their filamentous counterparts such as Streptomyces. From our collection of nonfilamentous actinobacteria isolated from sandstone, an Arthrobacter strain was found to produce a new cyclic peptide arthroamide (1) together with the known compound turnagainolide A (2). These compounds inhibited the quorum sensing signaling of Staphylococcus aureus in the submicromolar to micromolar range.
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