Fungicidal activity of fluopicolide for suppression of Phytophthora capsici on squash

The efficacy of a new fungicide fluopicolide in suppression of Phytophthora blight caused by Phytophthora capsici was evaluated under laboratory and field conditions. Studies with 51 P. capsici isolates from vegetable crops in Georgia, USA, indicated that 5.9% of the isolates were resistant, 19.6% were inter-mediately sensitive, and 74.5% were sensitive to 100 mu g ml(-1) of mefenoxam based on in vitro mycelial growth. EC50 values of fluopicolide in inhibiting mycelial growth of 25 isolates, representing resistant, inter-mediately sensitive, and sensitive to mefenoxam, ranged from 0.05 to 0.35 mu g ml(-1) with an average of 0.2 mu g ml(-1) EC50 values of fluopicolide in suppressing zoospore germination and sporangium production of the 25 isolates ranged from 1.1 to 4.5 mu g ml(-1) and 0.3-9.0 mu g ml(-1), respectively. Evaluation of a collection of 150 P. capsici isolates from vegetables and irrigation ponds found none of the isolates were resistant to 10 mu g ml(-1) of fluopicolide. Field experiments were conducted to determine the efficacy and application methods of fluopicolide for control of P. capsici on squash in spring 2007 and 2009. Fluopicolide applied through drip irrigation or as a foliar spray at 86.6 or 115.4 g ha(-1) consistently provided significant disease reduction and increased squash yield. Results with fluopicolide were similar or slightly superior to mefenoxam applied at recommended rate. Fluopicolide applied at 57.7 g ha(-1) did not provide consistent satisfactory disease suppression. The results indicated that fluopicolide was effective in suppression of different stages of the life cycle of P. capsici and could be a viable alternative to mefenoxam for managing Phytophthora blight in squash production. (C) 2010 Elsevier Ltd. All rights reserved.