4.5 Review

Organotypic liver culture models: Meeting current challenges in toxicity testing

Related references

Note: Only part of the references are listed.
Review Engineering, Biomedical

The Role of Body-on-a-Chip Devices in Drug and Toxicity Studies

M. B. Esch et al.

ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, VOL 13 (2011)

Article Gastroenterology & Hepatology

Human Hepatic Stem Cell and Maturational Liver Lineage Biology

Rachael Turner et al.

HEPATOLOGY (2011)

Review Cell Biology

Microfluidic devices for in vitro studies on liver drug metabolism and toxicity

Paul M. van Midwoud et al.

INTEGRATIVE BIOLOGY (2011)

Editorial Material Multidisciplinary Sciences

A LIVING SYSTEM ON A CHIP

Monya Baker

NATURE (2011)

Article Multidisciplinary Sciences

Using Nuclear Receptor Activity to Stratify Hepatocarcinogens

Imran Shah et al.

PLOS ONE (2011)

Article Biochemical Research Methods

Luciferin IPA-Based Higher Throughput Human Hepatocyte Screening Assays for CYP3A4 Inhibition and Induction

Utkarsh Doshi et al.

JOURNAL OF BIOMOLECULAR SCREENING (2011)

Article Gastroenterology & Hepatology

Isolation of periportal, midlobular, and centrilobular rat liver sinusoidal endothelial cells enables study of zonated drug toxicity

Guanhua Xie et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2010)

Article Pharmacology & Pharmacy

A microfluidic hepatic coculture platform for cell-based drug metabolism studies

Eric Novik et al.

BIOCHEMICAL PHARMACOLOGY (2010)

Review Pharmacology & Pharmacy

In Vitro Evaluation of Potential Hepatotoxicity Induced by Drugs

M. J. Gomez-Lechon et al.

CURRENT PHARMACEUTICAL DESIGN (2010)

Review Developmental Biology

Mechanical control of tissue and organ development

Tadanori Mammoto et al.

DEVELOPMENT (2010)

Article Pharmacology & Pharmacy

Assessment of a Micropatterned Hepatocyte Coculture System to Generate Major Human Excretory and Circulating Drug Metabolites

Wendy WeiWei Wang et al.

DRUG METABOLISM AND DISPOSITION (2010)

Article Environmental Sciences

In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project

Richard S. Judson et al.

ENVIRONMENTAL HEALTH PERSPECTIVES (2010)

Review Biochemistry & Molecular Biology

Three-dimensional culture of hepatocytes for prediction of drug-induced hepatotoxicity

Qin Meng

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2010)

Article Biochemistry & Molecular Biology

Inhibition of hepatic mitochondrial aldehyde dehydrogenase by carbon tetrachloride through JNK-mediated phosphorylation

Kwan-Hoon Moon et al.

FREE RADICAL BIOLOGY AND MEDICINE (2010)

Article Gastroenterology & Hepatology

Generation of Functional Human Hepatic Endoderm from Human Induced Pluripotent Stem Cells

Gareth J. Sullivan et al.

HEPATOLOGY (2010)

Article Medicine, Research & Experimental

Hypoxia and reoxygenation of primary human hepatocytes induce proteome changes of glucose metabolism, oxidative protection and peroxisomal function

Christoph W. Strey et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2010)

Article Biotechnology & Applied Microbiology

Alkoxyresorufin O-dealkylase assay using a rat hepatocyte spheroid microarray

Yusuke Sakai et al.

JOURNAL OF BIOSCIENCE AND BIOENGINEERING (2010)

Review Gastroenterology & Hepatology

Autophagy in liver diseases

Pierre-Emmanuel Rautou et al.

JOURNAL OF HEPATOLOGY (2010)

Article Biochemistry & Molecular Biology

Three-dimensional structured illumination microscopy of liver sinusoidal endothelial cell fenestrations

Victoria C. Cogger et al.

JOURNAL OF STRUCTURAL BIOLOGY (2010)

Review Environmental Sciences

VIRTUAL TISSUES IN TOXICOLOGY

Imran Shah et al.

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS (2010)

Review Environmental Sciences

TOXICITY TESTING IN THE 21ST CENTURY: A VISION AND A STRATEGY

Daniel Krewski et al.

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS (2010)

Article Biochemical Research Methods

Perfused multiwell plate for 3D liver tissue engineering

Karel Domansky et al.

LAB ON A CHIP (2010)

Review Biochemical Research Methods

Microfluidic cell culture systems for drug research

Min-Hsien Wu et al.

LAB ON A CHIP (2010)

Review Pharmacology & Pharmacy

Xenobiotic, Bile Acid, and Cholesterol Transporters: Function and Regulation

Curtis D. Klaassen et al.

PHARMACOLOGICAL REVIEWS (2010)

Editorial Material Toxicology

The Vision of Toxicity Testing in the 21st Century: Moving from Discussion to Action

Melvin E. Andersen et al.

TOXICOLOGICAL SCIENCES (2010)

Review Pharmacology & Pharmacy

Stem cell-derived hepatocytes and their use in toxicology

Christiane Guguen-Guillouzo et al.

TOXICOLOGY (2010)

Article Pharmacology & Pharmacy

Predicting Drug-Drug Interactions: An FDA Perspective

Lei Zhang et al.

AAPS JOURNAL (2009)

Article Hematology

Human IL-8 Regulates Smooth Muscle Cell VCAM-1 Expression in Response to Endothelial Cells Exposed to Atheroprone Flow

Nicole E. Hastings et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2009)

Review Biochemistry & Molecular Biology

Multifaceted role of Rho, Rac, Cdc42 and Ras in intercellular junctions, lessons from toxins

Michel R. Popoff et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)

Article Engineering, Biomedical

Engineering liver tissue spheroids with inverted colloidal crystal scaffolds

Jungwoo Lee et al.

BIOMATERIALS (2009)

Review Biotechnology & Applied Microbiology

Transcription factors: their potential as targets for an individualized therapeutic approach to cancer

C. Mees et al.

CANCER GENE THERAPY (2009)

Article Cell & Tissue Engineering

E-Cadherin Protects Primary Hepatocyte Spheroids From Cell Death by a Caspase-Independent Mechanism

Jennifer L. Luebke-Wheeler et al.

CELL TRANSPLANTATION (2009)

Article Pharmacology & Pharmacy

Impact of Infectious and Inflammatory Disease on Cytochrome P450-Mediated Drug Metabolism and Pharmacokinetics

E. T. Morgan

CLINICAL PHARMACOLOGY & THERAPEUTICS (2009)

Article Biochemical Research Methods

High Throughput Optimization of Stem Cell Microenvironments

Fan Yang et al.

COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (2009)

Review Biochemistry & Molecular Biology

Design and Application of Microfluidic Systems for In Vitro Pharmacokinetic Evaluation of Drug Candidates

T. J. Maguire et al.

CURRENT DRUG METABOLISM (2009)

Review Cell Biology

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

Bryan T. MacDonald et al.

DEVELOPMENTAL CELL (2009)

Review Gastroenterology & Hepatology

New insights into liver stem cells

E. Gaudio et al.

DIGESTIVE AND LIVER DISEASE (2009)

Review Biochemistry & Molecular Biology

Liver tissue engineering in the evaluation of drug safety

Ajit Dash et al.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2009)

Article Biochemistry & Molecular Biology

Cholangiocyte proliferation and liver fibrosis

Shannon S. Glaser et al.

EXPERT REVIEWS IN MOLECULAR MEDICINE (2009)

Article Gastroenterology & Hepatology

Differentiation and Transplantation of Human Embryonic Stem Cell-Derived Hepatocytes

Hesham Basma et al.

GASTROENTEROLOGY (2009)

Review Genetics & Heredity

Modelling tissues in 3D: the next future of pharmaco-toxicology and food research?

Giovanna Mazzoleni et al.

GENES AND NUTRITION (2009)

Article Cell Biology

Cell polarity triggered by cell-cell adhesion via E-cadherin

Ravi A. Desai et al.

JOURNAL OF CELL SCIENCE (2009)

Review Pharmacology & Pharmacy

Sex Differences in the Expression of Hepatic Drug Metabolizing Enzymes

David J. Waxman et al.

MOLECULAR PHARMACOLOGY (2009)

Review Cell Biology

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

Ning Wang et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)

Review Immunology

Liver architecture, cell function, and disease

Hiromi Ishibashi et al.

SEMINARS IN IMMUNOPATHOLOGY (2009)

Article Pathology

Phytol-induced Hepatotoxicity in Mice

John T. Mackie et al.

TOXICOLOGIC PATHOLOGY (2009)

Article Toxicology

ECVAM's ongoing activities in the area of acute oral toxicity

Agnieszka Kinsner-Ovaskainen et al.

TOXICOLOGY IN VITRO (2009)

Article Toxicology

Functional expression, inhibition and induction of CYP enzymes in HepaRG cells

Miia Turpeinen et al.

TOXICOLOGY IN VITRO (2009)

Review Biochemical Research Methods

Stem Cells in Drug Discovery, Tissue Engineering, and Regenerative Medicine: Emerging Opportunities and Challenges

Victor Sanjit Nirmalanandhan et al.

JOURNAL OF BIOMOLECULAR SCREENING (2009)

Article Biochemical Research Methods

Profiling Bioactivity of the ToxCast Chemical Library Using BioMAP Primary Human Cell Systems

Keith A. Houck et al.

JOURNAL OF BIOMOLECULAR SCREENING (2009)

Article Pharmacology & Pharmacy

Comparison of immortalized Fa2N-4 cells and human hepatocytes as in vitro models for cytochrome P450 induction

Niresh Hariparsad et al.

DRUG METABOLISM AND DISPOSITION (2008)

Article Pharmacology & Pharmacy

Evaluation of HepaRG cells as an in vitro model for human drug metabolism studies

Kajsa P. Kanebratt et al.

DRUG METABOLISM AND DISPOSITION (2008)

Review Biochemistry & Molecular Biology

Evolving concepts in liver tissue modeling and implications for in vitro toxicology

Andre Guillouzo et al.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2008)

Review Biochemistry & Molecular Biology

An update on metabolism studies using human hepatocytes in primary culture

Maria Jose Gomez-Lechon et al.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2008)

Article Cell Biology

Differentiation of mouse and human embryonic stem cells into hepatic lineages

Nobuaki Shiraki et al.

GENES TO CELLS (2008)

Article Gastroenterology & Hepatology

Sinusoidal endothelial cells prevent rat stellate cell activation and promote reversion to quiescence

Laurie D. DeLeve et al.

HEPATOLOGY (2008)

Article Gastroenterology & Hepatology

The Stem Cell Niche of Human Livers: Symmetry Between Development and Regeneration

Lili Zhang et al.

HEPATOLOGY (2008)

Article Multidisciplinary Sciences

Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signaling

David C. Hay et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Cell & Tissue Engineering

Efficient differentiation of functional hepatocytes from human embryonic stem cells

Sadhana Agarwal et al.

STEM CELLS (2008)

Review Pharmacology & Pharmacy

Understanding mechanisms of toxicity: Insights from drug discovery research

Keith A. Houck et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2008)

Review Pharmacology & Pharmacy

Quantitative interpretation of human biomonitoring data

Harvey J. Clewell et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2008)

Review Oncology

Wnt signalling and its impact on development and cancer

Alexandra Klaus et al.

NATURE REVIEWS CANCER (2008)

Article Cell Biology

Chondroitin sulfate sulfation motifs as putative biomarkers for isolation of articular cartilage progenitor cells

Anthony J. Hayes et al.

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2008)

Article Biotechnology & Applied Microbiology

Microscale culture of human liver cells for drug development

Salman R. Khetani et al.

NATURE BIOTECHNOLOGY (2008)

Article Gastroenterology & Hepatology

Wnt/beta-catenin signaling mediates oval cell response in rodents

Udayan Apte et al.

HEPATOLOGY (2008)

Article Pharmacology & Pharmacy

HepaRG cells as an in vitro model for evaluation of cytochrome p450 induction in humans

Kajsa P. Kanebratt et al.

DRUG METABOLISM AND DISPOSITION (2008)

Review Cell Biology

Activation of stem cells in hepatic diseases

T. G. Bird et al.

CELL AND TISSUE RESEARCH (2008)

Article Gastroenterology & Hepatology

Wnt/β-catenin signaling in murine hepatic transit amplifying progenitor cells

Min Hu et al.

GASTROENTEROLOGY (2007)

Review Gastroenterology & Hepatology

Hepatic microvasculature in liver injury

Laurie D. DeLeve

SEMINARS IN LIVER DISEASE (2007)

Article Biochemistry & Molecular Biology

Constitutive androstane receptor-vitamin D receptor crosstalk:: Consequence on CYP24 gene expression

Amélie Moreau et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Article Cell & Tissue Engineering

Dynamics of the self-assembly of complex cellular aggregates on micromolded nonadhesive hydrogels

Anthony P. Napolitano et al.

TISSUE ENGINEERING (2007)

Article Biotechnology & Applied Microbiology

An artificial liver sinusoid with a microfluidic endothelial-like barrier for primary hepatocyte culture

Philip J. Lee et al.

BIOTECHNOLOGY AND BIOENGINEERING (2007)

Article Engineering, Biomedical

Human hepatoblast phenotype maintained by hyaluronan hydrogels

William S. Turner et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS (2007)

Article Gastroenterology & Hepatology

Adipose tissue-derived mesenchymal stem cells as a source of human hepatocytes

Agnieszka Banas et al.

HEPATOLOGY (2007)

Article Biochemistry & Molecular Biology

The human hepatoma HepaRG cells: A highly differentiated model for studies of liver metabolism and toxicity of xenobiotics

Andre Guillouzo et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2007)

Article Gastroenterology & Hepatology

Cholangiocyte biology

Pamela Tietz Bogert et al.

CURRENT OPINION IN GASTROENTEROLOGY (2007)

Article Pharmacology & Pharmacy

Drug interaction studies: Study design, data analysis, and implications for dosing and labeling

S-M Huang et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2007)

Review Toxicology

Role of the Kupffer cell in mediating hepatic toxicity and carcinogenesis

Ruth A. Roberts et al.

TOXICOLOGICAL SCIENCES (2007)

Article Gastroenterology & Hepatology

Transforming growth factor-beta differentially regulates oval cell and hepatocyte proliferation

Lananh N. Nguyen et al.

HEPATOLOGY (2007)

Review Biochemistry & Molecular Biology

GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo

Xose R. Bustelo et al.

BIOESSAYS (2007)

Article Cell & Tissue Engineering

Hepatic differentiation potential of commercially available human mesenchymal stem cells

Shin-Yeu Ong et al.

TISSUE ENGINEERING (2006)

Article Gastroenterology & Hepatology

Liver regeneration in acute severe liver impairment: a clinicopathological correlation study

Aezam Katoonizadeh et al.

LIVER INTERNATIONAL (2006)

Article Gastroenterology & Hepatology

Rat liver endothelial cells isolated by anti-CD31 immunomagnetic separation lack fenestrae and sieve plates

Laurie D. DeLeve et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2006)

Review Biochemistry & Molecular Biology

Wnt/β-catenin signaling in development and disease

Hans Clevers

Article Gastroenterology & Hepatology

Transcriptional regulation of stellate cell activation

Scott L. Friedman

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2006)

Article Biochemistry & Molecular Biology

Matrix elasticity directs stem cell lineage specification

Adam J. Engler et al.

Review Veterinary Sciences

The isolated perfused rat liver: standardization of a time-honoured model

M. Bessems et al.

LABORATORY ANIMALS (2006)

Review Gastroenterology & Hepatology

Cholangiocyte anion exchange and biliary bicarbonate excretion

Jesus M. Banales et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2006)

Article Gastroenterology & Hepatology

Bile acid interactions with cholangiocytes

Xuefeng Xia et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2006)

Article Gastroenterology & Hepatology

Cholangiocyte biology

PS Tietz et al.

CURRENT OPINION IN GASTROENTEROLOGY (2006)

Article Gastroenterology & Hepatology

Growth and differentiation of colony-forming human hepatocytes in vitro

C Yamasaki et al.

JOURNAL OF HEPATOLOGY (2006)

Article Pharmacology & Pharmacy

Characterization of cytochrome P450 expression in murine embryonic stem cell-derived hepatic tissue system

M Tsutsui et al.

DRUG METABOLISM AND DISPOSITION (2006)

Review Biochemistry & Molecular Biology

Hepatocyte cell lines:: their use, scope and limitations in drug metabolism studies

Jose V. Castell et al.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2006)

Review Multidisciplinary Sciences

Stem cells and their niches

KA Moore et al.

SCIENCE (2006)

Review Cell Biology

Capturing complex 3D tissue physiology in vitro

LG Griffith et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)

Review Chemistry, Multidisciplinary

CYP induction-mediated drug interactions: in vitro assessment and clinical implications

Jiunn H. Lin

PHARMACEUTICAL RESEARCH (2006)

Review Biochemistry & Molecular Biology

A microscale in vitro physiological model of the liver:: Predictive screens for drug metabolism and enzyme induction

A Sivaraman et al.

CURRENT DRUG METABOLISM (2005)

Review Cell Biology

The challenges of abundance: epithelial junctions and small GTPase signalling

VMM Braga et al.

CURRENT OPINION IN CELL BIOLOGY (2005)

Article Pharmacology & Pharmacy

Acetoacetate induces CYP2E1 protein and suppresses CYP2E1 mRNA in primary cultured rat hepatocytes

MA Abdelmegeed et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)

Article Medicine, Research & Experimental

TWEAK induces liver progenitor cell proliferation

A Jakubowski et al.

JOURNAL OF CLINICAL INVESTIGATION (2005)

Review Gastroenterology & Hepatology

The immunophysiology of biliary epithelium

G Fava et al.

SEMINARS IN LIVER DISEASE (2005)

Article Gastroenterology & Hepatology

Ethanol hinging exacerbates sinusoidal endothelial and parenchymal injury elicited by acetaminophen

RS McCuskey et al.

JOURNAL OF HEPATOLOGY (2005)

Article Biochemical Research Methods

Patterned cell culture inside microfluidic devices

SW Rhee et al.

LAB ON A CHIP (2005)

Article Pharmacology & Pharmacy

Induction of drug metabolism enzymes and MDR1 using a novel human hepatocyte cell line

JB Mills et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)

Review Multidisciplinary Sciences

Convergence of Wnt, β-catenin, and cadherin pathways

WJ Nelson et al.

SCIENCE (2004)

Article Pharmacology & Pharmacy

Kupffer cell-mediated IL-2 suppression of CYP3A activity in human hepatocytes

JA Sunman et al.

DRUG METABOLISM AND DISPOSITION (2004)

Article Gastroenterology & Hepatology

Rat liver sinusoidal endothelial cell phenotype is maintained by paracrine and autocrine regulation

LD DeLeve et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2004)

Review Pharmacology & Pharmacy

Dose-dependent transitions in mechanisms of toxicity

W Slikker et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2004)

Review Pharmacology & Pharmacy

Dose-dependent transitions in mechanisms of toxicity: case studies

W Slikker et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2004)

Article Gastroenterology & Hepatology

In vitro hepatic differentiation of human mesenchymal stem cells

KD Lee et al.

HEPATOLOGY (2004)

Article Multidisciplinary Sciences

Lhx2-/- mice develop liver fibrosis

E Wandzioch et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biotechnology & Applied Microbiology

Modeling mass transfer in hepatocyte spheroids via cell viability, spheroid size, and hepatocellular functions

R Glicklis et al.

BIOTECHNOLOGY AND BIOENGINEERING (2004)

Article Biotechnology & Applied Microbiology

Comparison of basal gene expression profiles and effects of hepatocarcinogens on gene expression in cultured primary human hepatocytes and HepG2 cells

AJ Harris et al.

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2004)

Review Biochemistry & Molecular Biology

Role of cytochrome P450-dependent arachidonic acid metabolites in liver physiology and pathophysiology

D Sacerdoti et al.

PROSTAGLANDINS & OTHER LIPID MEDIATORS (2003)

Review Biochemistry & Molecular Biology

Drug uptake systems in liver and kidney

JE van Montfoort et al.

CURRENT DRUG METABOLISM (2003)

Article Biotechnology & Applied Microbiology

Formation of steady-state oxygen gradients in vitro - Application to liver zonation

JW Allen et al.

BIOTECHNOLOGY AND BIOENGINEERING (2003)

Review Pharmacology & Pharmacy

Role of orphan nuclear receptors in the regulation of drug-metabolising enzymes

HB Wang et al.

CLINICAL PHARMACOKINETICS (2003)

Article Gastroenterology & Hepatology

Inducible differentiation and morphogenesis of bipotential liver cell lines from wild-type mouse embryos

H Strick-Marchand et al.

HEPATOLOGY (2002)

Review Gastroenterology & Hepatology

Functional heterogeneity of cholangiocytes

M Marzioni et al.

SEMINARS IN LIVER DISEASE (2002)

Review Oncology

Hepatic stem cells

S Forbes et al.

JOURNAL OF PATHOLOGY (2002)

Article Biotechnology & Applied Microbiology

A microfabricated array bioreactor for perfused 3D liver culture

MJ Powers et al.

BIOTECHNOLOGY AND BIOENGINEERING (2002)

Article Gastroenterology & Hepatology

Insulin signaling in the transcriptional and posttranscriptional regulation of CYP2E1 expression

KJ Woodcroft et al.

HEPATOLOGY (2002)

Article Toxicology

Forum - Mechanisms of hepatotoxicity

H Jaeschke et al.

TOXICOLOGICAL SCIENCES (2002)

Article Gastroenterology & Hepatology

Non-alcoholic fatty liver disease

P Angulo et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2002)

Review Pharmacology & Pharmacy

Alteration of drug biotransformation and elimination during infection and inflammation

KW Renton

PHARMACOLOGY & THERAPEUTICS (2001)

Article Pathology

Hepatic progenitor cells in hepatocellular adenomas

L Libbrecht et al.

AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2001)

Article Biochemistry & Molecular Biology

Shear stress-induced nitric oxide release triggers the liver regeneration cascade

JM Schoen et al.

NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2001)

Review Gastroenterology & Hepatology

History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells

A Geerts

SEMINARS IN LIVER DISEASE (2001)

Review Pharmacology & Pharmacy

Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation

EL LeCluyse

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2001)

Article Critical Care Medicine

Hepatic response to sepsis: Interaction between coagulation and inflammatory processes

JF Dhainaut et al.

CRITICAL CARE MEDICINE (2001)

Review Biochemistry & Molecular Biology

Prooxidant and antioxidant functions of nitric oxide in liver toxicity

JD Laskin et al.

ANTIOXIDANTS & REDOX SIGNALING (2001)