Journal
CRITICAL REVIEWS IN MICROBIOLOGY
Volume 36, Issue 2, Pages 168-177Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/10408410903530619
Keywords
Aspergillus fumigatus; single nucleotide polymorphisms; susceptibility; cytokines; toll like receptors
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Recently, a growing number of defined single nucleotide polymorphisms have been described that genetically determine susceptibility to A. fumigatus. This includes genes encoding for cytokines or chemokines and their receptors, toll-like receptor genes, and other genes involved in innate immunity. This review summarizes the current knowledge about the growing number of genetic markers and their relevance for the course and outcome of infections with A. fumigatus.
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