Journal
CRITICAL REVIEWS IN MICROBIOLOGY
Volume 36, Issue 3, Pages 195-211Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/10408411003604619
Keywords
Viral disease; mathematical modeling; epidemiology; infection control; regulatory policy
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Mathematical modeling can be used for the development and implementation of infection control policy to combat outbreaks and epidemics of communicable viral diseases. Here an outline is provided of basic concepts and approaches used in mathematical modeling and parameterization of disease transmission. The use of mathematical models is illustrated, using the 2001 UK foot-and-mouth disease (FMD) epidemic, the 2003 global severe acute respiratory syndrome (SARS) epidemic, and human influenza pandemics, as examples. This provides insights in the strengths, limitations, and weaknesses of the various models, and demonstrates their potential for supporting policy and decision making.
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