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A cytokine-mediated link between innate immunity, inflammation, and cancer
Wan-Wan Lin et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Trawling for treasure: tales of T-bet
Laurie H. Glimcher
NATURE IMMUNOLOGY (2007)
Requirement of bic/microRNA-155 for normal immune function
Antony Rodriguez et al.
SCIENCE (2007)
Colorectal neoplasia in Crohn's colitis:: a retrospective comparative study with ulcerative colitis
M. Svrcek et al.
HISTOPATHOLOGY (2007)
Sustained IL-6/STAT-3 signaling in cholangiocarcinoma cells due to SOCS-3 epigenetic silencing
Hajime Isomoto et al.
GASTROENTEROLOGY (2007)
Regulation of aicda expression and AID activity: Relevance to somatic Hypermutation and class switch DNA recombination
Zhenming Xu et al.
CRITICAL REVIEWS IN IMMUNOLOGY (2007)
Cellular senescence: when bad things happen to good cells
Judith Campisi et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
The DNA damage response, immunity and cancer
Stephan Gasser et al.
SEMINARS IN CANCER BIOLOGY (2006)
Escherichia coli induces DNA double-strand breaks in eukaryotic cells
Jean-Philippe Nougayrede et al.
SCIENCE (2006)
Role of Toll-like receptors in spontaneous commensal-dependent colitis
Seth Rakoff-Nahoum et al.
IMMUNITY (2006)
The multifaceted mismatch-repair system
J Jiricny
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
The DNA damage response arouses the immune system
S Gasser et al.
CANCER RESEARCH (2006)
Unique microRNA molecular profiles in lung cancer diagnosis and prognosis
N Yanaihara et al.
CANCER CELL (2006)
The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase
V Vartanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Endogenous reactive intermediates as modulators of cell signaling and cell death
JD West et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2006)
The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms
C Bavik et al.
CANCER RESEARCH (2006)
Association of interleukin-1 beta gene polymorphisms with precancerous gastric lesions in African Americans and Caucasians
J Zabaleta et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2006)
Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines
Fanyin Meng et al.
GASTROENTEROLOGY (2006)
Repair of formamidopyrimidines in DNA involves different glycosylases - Role of the OGG1, NTH1, and NEIL1 enzymes
JP Hu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Limiting inflammatory responses during activation of innate immunity
JH Han et al.
NATURE IMMUNOLOGY (2005)
Direct repair of the exocyclic DNA adduct 1,N6-ethenoadenine by the DNA repair AlkB proteins
Y Mishina et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
NFκB:: Linking inflammation and immunity to cancer development and progression
M Karin et al.
NATURE REVIEWS IMMUNOLOGY (2005)
The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor
S Gasser et al.
NATURE (2005)
The role of MLH1, MSH2 and MSH6 in the development of multiple colorectal cancers
DA Lawes et al.
BRITISH JOURNAL OF CANCER (2005)
MicroRNA gene expression deregulation in human breast cancer
MV Iorio et al.
CANCER RESEARCH (2005)
Immunoselective pressure and human leukocyte antigen class I antigen machinery defects in microsatellite unstable colorectal cancers
M Kloor et al.
CANCER RESEARCH (2005)
Basal cell carcinoma and variants in genes coding for immune response, DNA repair, folate and iron metabolism
F Festa et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2005)
CD4+CD25+ regulatory lymphocytes induce regression of intestinal tumors in ApcMin/+ mice
SE Erdman et al.
CANCER RESEARCH (2005)
Microsatellite instability in colorectal cancer is associated with local lymphocyte infiltration and low frequency of distant metastases
A Buckowitz et al.
BRITISH JOURNAL OF CANCER (2005)
Clinical significance of microsatellite instability in the inflamed mucosa for the prediction of colonic neoplasms in patients with ulcerative colitis
T Tahara et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2005)
Helicobacter pylori and gastric cancer:: A new paradigm for inflammation-associated epithelial cancers
J Houghton et al.
GASTROENTEROLOGY (2005)
Innate immune recognition of the extracellular mucosal pathogen, Helicobacter pylori
RL Ferrero
MOLECULAR IMMUNOLOGY (2005)
Accumulation of miR-155 and BIC RNA in human B cell lymphomas
PS Eis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Delineation of the chemical pathways underlying nitric oxide-induced homologous recombination in mammalian cells
T Kiziltepe et al.
CHEMISTRY & BIOLOGY (2005)
Systematic review of microsatellite instability and colorectal cancer prognosis
S Popat et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
DNA glycosylase activities for thymine residues oxidized in the methyl group are functions of the hNElL1 and hNTH1 enzymes in human cells
QM Zhang et al.
DNA REPAIR (2005)
Intragenic tandem repeats generate functional variability
KJ Verstrepen et al.
NATURE GENETICS (2005)
Endogenous DNA damage in humans: a review of quantitative data
R De Bont et al.
MUTAGENESIS (2004)
Suppression of intestinal polyposis in Apcmin/+ mice by targeting the nitric oxide or poly(ADP-ribose) pathways
JG Mabley et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2004)
Tumour-infiltrating lymphocytes in colorectal cancer with microsatellite instability are activated and cytotoxic
SM Phillips et al.
BRITISH JOURNAL OF SURGERY (2004)
The significance of the Wnt pathway in the pathology of human cancers
RZ Karim et al.
PATHOLOGY (2004)
Stereoselective excision of thymine glycol lesions by mammalian cell extracts
MM McTigue et al.
DNA REPAIR (2004)
Inflammation and cancer - I. Rodent models of infectious gastrointestinal and liver cancer
AB Rogers et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2004)
Reactive nitrogen species in the chemical biology of inflammation
PC Dedon et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2004)
NF-κB functions as a tumour promoter in inflammation-associated cancer
E Pikarsky et al.
NATURE (2004)
Carcinogenic properties of proteins with pro-inflammatory activity from Streptococcus infantarius (formerly S.bovis)
J Biarc et al.
CARCINOGENESIS (2004)
Cytokine gene polymorphisms influence mucosal cytokine expression, gastric inflammation, and host specific colonisation during Helicobacter pylori infection
R Rad et al.
GUT (2004)
Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumor-prone mice defective in both the Myh and Ogg1 DNA glycosylases
MT Russo et al.
CANCER RESEARCH (2004)
Stereoselective excision of thymine glycol from oxidatively damaged DNA
H Miller et al.
NUCLEIC ACIDS RESEARCH (2004)
Finishing the euchromatic sequence of the human genome
FS Collins et al.
NATURE (2004)
The three Es of cancer immunoediting
GP Dunn et al.
ANNUAL REVIEW OF IMMUNOLOGY (2004)
Repair and genetic consequences of endogenous DNA base damage in mammalian cells
DE Barnes et al.
ANNUAL REVIEW OF GENETICS (2004)
Repair of oxidized bases in DNA bubble structures by human DNA glycosylases NEIL1 and NEIL2
H Dou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Defect of tumour necrosis factor-α (TNF-α) production and TNF-α-induced ICAM-1-expression in BRCA1 mutations carriers
CC Zielinski et al.
BREAST CANCER RESEARCH AND TREATMENT (2003)
Imbalanced secondary mucosal antioxidant response in inflammatory bowel disease
L Kruidenier et al.
JOURNAL OF PATHOLOGY (2003)
Intestinal oxidative damage in inflammatory bowel disease: semi-quantification, localization, and association with mucosal antioxidants
L Kruidenier et al.
JOURNAL OF PATHOLOGY (2003)
Autosomal recessive colorectal adenomatous polyposis due to inherited mutations of MYH
JR Sampson et al.
LANCET (2003)
Promoter methylation of E-cadherin gene in gastric mucosa associated with Helicobacter pylori infection and in gastric cancer
AOO Chan et al.
GUT (2003)
Substrate specificity of human endonuclease III (hNTH1) - Effect of human APE1 on hNTH1 activity
DR Marenstein et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Toll receptors and pathogen resistance
K Takeda et al.
CELLULAR MICROBIOLOGY (2003)
Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH
OM Sieber et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Mutagenicity of reactive oxygen and nitrogen species as detected by co-culture of activated inflammatory leukocytes and AS52 cells
HW Kim et al.
CARCINOGENESIS (2003)
Regulation of the IRF-1 tumour modifier during the response to genotoxic stress involves an ATM-dependent signalling pathway
J Pamment et al.
ONCOGENE (2002)
Natural selection of tumor variants in the generation of tumor escape phenotypes
HT Khong et al.
NATURE IMMUNOLOGY (2002)
Biallelic germline mutations in MYH predispose to multiple colorectal adenoma and somatic G:C→T:A mutations
S Jones et al.
HUMAN MOLECULAR GENETICS (2002)
Cancer immunoediting: from immunosurveillance to tumor escape
GP Dunn et al.
NATURE IMMUNOLOGY (2002)
Medical progress:: Helicobacter pylori infection
S Suerbaum et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
Strong HLA-DR expression in microsatellite stable carcinomas of the large bowel is associated with good prognosis
T Lovig et al.
BRITISH JOURNAL OF CANCER (2002)
AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli
PO Falnes et al.
NATURE (2002)
Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage
SC Trewick et al.
NATURE (2002)
Targeted deletion of mNth1 reveals a novel DNA repair enzyme activity
MTA Ocampo et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Identification of 5-formyluracil DNA glycosylase activity of human hNTH1 protein
I Miyabe et al.
NUCLEIC ACIDS RESEARCH (2002)
A novel human DNA glycosylase that removes oxidative DNA damage and is homologous to Escherichia coli endonuclease VIII
V Bandaru et al.
DNA REPAIR (2002)
Oxidative stress inactivates the human DNA mismatch repair system
CL Chang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2002)
Aberrant methylation of the ATM promoter correlates with increased radiosensitivity in a human colorectal tumor cell line
WJ Kim et al.
ONCOGENE (2002)
Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA
TK Hazra et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Inherited variants of MYH associated with somatic G:C→T:A mutations in colorectal tumors
N Al-Tassan et al.
NATURE GENETICS (2002)
Frameshift-mutation-derived peptides as tumor-specific antigens in inherited and spontaneous colorectal cancer
I Saeterdal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
The cytolethal distending toxins induce DNA damage and cell cycle arrest
X Cortes-Bratti et al.
TOXICON (2001)
Substrate specificity and excision kinetics of Escherichia coli endonuclease VIII (Nei) for modified bases in DNA damaged by free radicals
M Dizdaroglu et al.
BIOCHEMISTRY (2001)
Helicobacter pylori infection and the development of gastric cancer.
N Uemura et al.
NEW ENGLAND JOURNAL OF MEDICINE (2001)
Inflammation, carcinogenesis and cancer
FA Fitzpatrick
INTERNATIONAL IMMUNOPHARMACOLOGY (2001)
Frameshift peptide-derived T-cell epitopes: a source of novel tumor-specific antigens
M Linnebacher et al.
INTERNATIONAL JOURNAL OF CANCER (2001)
Microsatellite instability and high content of activated cytotoxic lymphocytes identify colon cancer patients with a favorable prognosis
M Guidoboni et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
Stimulation of human endonuclease III by Y box-binding protein 1 (DNA-binding protein B) - Interaction between a base excision repair enzyme and a transcription factor
DR Marenstein et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Human endonuclease III acts preferentially on DNA damage opposite guanine residues in DNA
L Eide et al.
BIOCHEMISTRY (2001)
The importance of interleukin 1β in Helicobacter pylori associated disease
EM El-Omar
GUT (2001)
Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family
A Steinle et al.
IMMUNOGENETICS (2001)
IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity
V Shankaran et al.
NATURE (2001)
Oxidative stress increases MICA and MICB gene expression in the human colon carcinoma cell line (CaCo-2)
K Yamamoto et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2001)
NF-kappa B: a key role in inflammatory diseases
PP Tak et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
Identification of repair enzymes for 5-formyluracil in DNA -: Nth, Nei, and MutM proteins of Escherichia coli
QM Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Comparison of substrate specificities of Escherichia coli endonuclease III and its mouse homologue (mNTH1) using defined oligonucleotide substrates
K Asagoshi et al.
BIOCHEMISTRY (2000)
Recognition of formamidopyrimidine by Escherichia coli and mammalian thymine glycol glycosylases -: Distinctive paired base effects and biological and mechanistic implications
K Asagoshi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice
O Minowa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
The COX-2 inhibitor nimesulide suppresses superoxide and 8-hydroxy-deoxyguanosine formation, and stimulates apoptosis in mucosa during early colonic inflammation in rats
D Tardieu et al.
CARCINOGENESIS (2000)
Interleukin-1 polymorphisms associated with increased risk of gastric cancer
EM El-Omar et al.
NATURE (2000)
Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria
T Ohtsubo et al.
NUCLEIC ACIDS RESEARCH (2000)