Journal
CRITICAL CARE MEDICINE
Volume 38, Issue -, Pages S169-S174Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/CCM.0b013e3181de0c60
Keywords
acute kidney injury; acute kidney failure; drug-induced
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Funding
- Hospira
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Acute kidney injury is common in critically ill patients, with an incidence of 20% to 30%. It has been associated with increased mortality, hospital length of stay, and total cost. A number of strategies may be beneficial in identifying at-risk patients. In addition, using preventive measures and avoiding nephrotoxic medications are paramount in reducing the overall incidence. Although multifactorial, drug-induced acute kidney injury may account for up to 25% of all cases of acute kidney injury in this population. This review focuses on the mechanisms of drug-induced acute kidney injury in critically ill adults and offers preventive strategies when appropriate. (Crit Care Med 2010; 38[Suppl.]:S169-S174)
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