Non-innocent ligands in bioinorganic chemistry-An overview

This review touches the most common instances where non-innocent (suspect) behaviour of redoxactive ligands, either substrates or supporting components, is observed in a biochemical context. These ligands include the O-2/O-2(center dot-)/O-2(2-), NO+/NO center dot/NO-, o-quinone/o-semiquinone/catecholate and tyrosyl/tyrosinate reclox systems, the tetrapyrrole (porphyrinic) ligands, the pterins and flavins, and the dithiolene/ene-dithiolate ligands in molybdo- and tungstopterin. These non-innocent ligands are discussed in their interaction with biological iron, copper, manganese, molybdenum or tungsten centers. (C) 2010 Elsevier B.V. All rights reserved.