Journal
CONTRAST MEDIA & MOLECULAR IMAGING
Volume 8, Issue 1, Pages 92-95Publisher
WILEY-BLACKWELL
DOI: 10.1002/cmmi.1481
Keywords
nuclear magnetic resonance (NMR); magnetic resonance imaging (MRI); gadolinium oxide; contrast agent
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In this communication, we demonstrate that there is an optimum gadolinium oxide (Gd2O3) nanoparticle size of 2.3 nm; in the presence of Gd2O3 particles smaller and larger than this critical size, the spin-lattice relaxation rate (T-1 = 1/r(1)) of water protons at 7.0 T drastically decreases. Since r(1) is directly related to the quality of magnetic resonance imaging, the results presented here have significant implications for clinical diagnostics. Copyright (C) 2012 John Wiley & Sons, Ltd.
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