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Does Response Inhibition Have Pre- and Postdiagnostic Utility in Parkinson's Disease?

Journal

JOURNAL OF MOTOR BEHAVIOR
Volume 47, Issue 1, Pages 29-45

Publisher

ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
DOI: 10.1080/00222895.2014.941784

Keywords

Parkinson's disease; biomarkers; individualized treatment; response inhibition; impulse control disorders

Funding

  1. W AMP
  2. B Miller scholarship from the Neurological Foundation of New Zealand

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. Parkinson's disease (Pd) is the second most prevalent degenerative neurological condition worldwide. Improving and sustaining quality of life is an important goal for Parkinson's patients. Key areas of focus to achieve this goal include earlier diagnosis and individualized treatment. In this review the authors discuss impulse control in Pd and examine how measures of impulse control from a response inhibition task may provide clinically useful information (a) within an objective test battery to aid earlier diagnosis of Pd and (b) in postdiagnostic Pd, to better identify individuals at risk of developing impulse control disorders with dopaminergic medication.

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