Journal
CONNECTIVE TISSUE RESEARCH
Volume 50, Issue 2, Pages 132-138Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/03008200802585622
Keywords
Matrix Metalloproteinases; Skin Ageing; Connective Tissue Degradation; Photoageing; Chronological Ageing; Extracellular Matrix
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Matrix metalloproteinases are a family of ubiquitous endopeptidases playing a role in many different physiological and pathological processes in the skin. They are also involved in cutaneous ageing. This review summarizes the features and regulation of these enzymes and presents an overview of the molecular mechanisms of both intrinsic and extrinsic skin ageing presents. The role of matrix metalloproteinases in skin ageing is discussed in detail.
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