Related references
Note: Only part of the references are listed.Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling
Aashish Manglik et al.
CELL (2015)
G Protein-coupled Receptor (GPCR) Signaling via Heterotrimeric G Proteins from Endosomes
Nikoleta G. Tsvetanova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Distinct Spatial Ca2+ Signatures Selectively Activate Different NFAT Transcription Factor Isoforms
Pulak Kar et al.
MOLECULAR CELL (2015)
Structural basis for nucleotide exchange in heterotrimeric G proteins
Ron O. Dror et al.
SCIENCE (2015)
In vivo model with targeted cAMP biosensor reveals changes in receptor-microdomain communication in cardiac disease
Julia U. Sprenger et al.
NATURE COMMUNICATIONS (2015)
Calcium influx activates adenylyl cyclase 8 for sustained insulin secretion in rat pancreatic beta cells
Haiqiang Dou et al.
DIABETOLOGIA (2015)
PDZ Protein Regulation of G Protein-Coupled Receptor Trafficking and Signaling Pathways
Henry A. Dunn et al.
MOLECULAR PHARMACOLOGY (2015)
Spatial and Temporal Aspects of Signaling by G-Protein-Coupled Receptors
Martin J. Lohse et al.
MOLECULAR PHARMACOLOGY (2015)
Adenylate cyclase-centred microdomains
Dermot M. F. Cooper et al.
BIOCHEMICAL JOURNAL (2014)
Single-molecule imaging revealed dynamic GPCR dimerization
Rinshi S. Kasai et al.
CURRENT OPINION IN CELL BIOLOGY (2014)
Heterologous Regulation of Mu-Opioid (MOP) Receptor Mobility in the Membrane of SH-SY5Y Cells
Kevin Carayon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Can we decipher the information content contained within cyclic nucleotide signals?
Thomas C. Rich et al.
JOURNAL OF GENERAL PHYSIOLOGY (2014)
Endosomal generation of cAMP in GPCR signaling
Jean-Pierre Vilardaga et al.
NATURE CHEMICAL BIOLOGY (2014)
Fine tuning of sub-millisecond conformational dynamics controls metabotropic glutamate receptors agonist efficacy
Linnea Olofsson et al.
NATURE COMMUNICATIONS (2014)
Calmodulin-controlled spatial decoding of oscillatory Ca2+ signals by calcineurin
Sohum Mehta et al.
ELIFE (2014)
A Brief History of G-Protein Coupled Receptors (Nobel Lecture)
Robert J. Lefkowitz
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)
The Structural Basis of G-Protein-Coupled Receptor Signaling (Nobel Lecture)
Brian Kobilka
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)
AKAP79, PKC, PKA and PDE4 participate in a Gq-linked muscarinic receptor and adenylate cyclase 2 cAMP signalling complex
Jia X. Shen et al.
BIOCHEMICAL JOURNAL (2013)
The Dynamic Process of β2-Adrenergic Receptor Activation
Rie Nygaard et al.
CELL (2013)
Precision vs Flexibility in GPCR signaling
Matthias Elgeti et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
CELL BIOLOGY Receptor signals come in waves
Martin J. Lohse et al.
NATURE (2013)
Molecular signatures of G-protein-coupled receptors
A. J. Venkatakrishnan et al.
NATURE (2013)
Single-molecule analysis of fluorescently labeled G-protein-coupled receptors reveals complexes with distinct dynamics and organization
Davide Calebiro et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Biomolecular Simulation: A Computational Microscope for Molecular Biology
Ron O. Dror et al.
ANNUAL REVIEW OF BIOPHYSICS, VOL 41 (2012)
Direct Binding Between Orai1 and AC8 Mediates Dynamic Interplay Between Ca2+ and cAMP Signaling
Debbie Willoughby et al.
SCIENCE SIGNALING (2012)
Comparison of the Activation Kinetics of the M3 Acetylcholine Receptor and a Constitutively Active Mutant Receptor in Living Cells
Carsten Hoffmann et al.
MOLECULAR PHARMACOLOGY (2012)
Fluorescence/Bioluminescence Resonance Energy Transfer Techniques to Study G-Protein-Coupled Receptor Activation and Signaling
Martin J. Lohse et al.
PHARMACOLOGICAL REVIEWS (2012)
Full characterization of GPCR monomer-dimer dynamic equilibrium by single molecule imaging
Rinshi S. Kasai et al.
JOURNAL OF CELL BIOLOGY (2011)
Crystal structure of the β2 adrenergic receptor-Gs protein complex
Soren G. F. Rasmussen et al.
NATURE (2011)
Decoding cytosolic Ca2+ oscillations
Anant B. Parekh
TRENDS IN BIOCHEMICAL SCIENCES (2011)
β-arrestin-mediated receptor trafficking and signal transduction
Sudha K. Shenoy et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2011)
Calcium Oscillations
Genevieve Dupont et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)
Gq-mediated Ca2+ signals inhibit adenylyl cyclases 5/6 in vascular smooth muscle cells
Kathrin von Hayn et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2010)
Dimerization in GPCR mobility and signaling
Martin J. Lohse
CURRENT OPINION IN PHARMACOLOGY (2010)
Differential Signaling of the Endogenous Agonists at the β2-Adrenergic Receptor
Susanne Reiner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Formation and dissociation of M1 muscarinic receptor dimers seen by total internal reflection fluorescence imaging of single molecules
Jonathan A. Hern et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
β2-Adrenergic Receptor Redistribution in Heart Failure Changes cAMP Compartmentation
Viacheslav O. Nikolaev et al.
SCIENCE (2010)
Signaling by internalized G-protein-coupled receptors
Davide Calebiro et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2010)
Fluorescence changes reveal kinetic steps of muscarinic receptor-mediated modulation of phosphoinositides and Kv7.2/7.3 K+ channels
Jill B. Jensen et al.
JOURNAL OF GENERAL PHYSIOLOGY (2009)
Real-time monitoring of cAMP levels in living endothelial cells: thrombin transiently inhibits adenylyl cyclase 6
R. C. Werthmann et al.
JOURNAL OF PHYSIOLOGY-LONDON (2009)
Fluorescence Resonance Energy Transfer Analysis of α2a-Adrenergic Receptor Activation Reveals Distinct Agonist-Specific Conformational Changes
A. Zuern et al.
MOLECULAR PHARMACOLOGY (2009)
Analysis of receptor oligomerization by FRAP microscopy
Sandra Dorsch et al.
NATURE METHODS (2009)
A G protein-coupled receptor at work: the rhodopsin model
Klaus Peter Hofmann et al.
TRENDS IN BIOCHEMICAL SCIENCES (2009)
Cytoplasmic cAMP concentrations in intact cardiac myocytes
Radu V. Iancu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2008)
Two protonation switches control rhodopsin activation in membranes
Mohana Mahalingam et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors
Martin J. Lohse et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2008)
Crystal structure of the human β2 adrenergic G-protein-coupled receptor
Soren G. F. Rasmussen et al.
NATURE (2007)
Organization and Ca2+ regulation of adenylyl cyclases in cAMP microdomains
Debbie Willoughby et al.
PHYSIOLOGICAL REVIEWS (2007)
Cyclic AMP imaging in adult cardiac myocytes reveals far-reaching β1-adrenergic but locally confined β2-adrenergic receptor-mediated signaling
Viacheslav O. Nikolaev et al.
CIRCULATION RESEARCH (2006)
GS activation is time-limiting in initiating receptor-mediated signaling
Peter Hein et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Distinct signaling profiles of β1 and β2 adrenergic receptor ligands toward adenylyl cyclase and mitogen-activated protein kinase reveals the pluridimensionality of efficacy
Segolene Galandrin et al.
MOLECULAR PHARMACOLOGY (2006)
Coupling ligand structure to specific conformational switches in the β2-adrenoceptor
Xiaojie Yao et al.
NATURE CHEMICAL BIOLOGY (2006)
Oscillations of cyclic AMP in hormone-stimulated insulin-secreting β-cells
O Dyachok et al.
NATURE (2006)
Building functional modules from molecular interactions
Klaus Peter Hofmann et al.
TRENDS IN BIOCHEMICAL SCIENCES (2006)
Dynamics of receptor/G protein coupling in living cells
P Hein et al.
EMBO JOURNAL (2005)
Interplay of Ca2+ and cAMP signaling in the insulin-secreting MIN6 β-cell line
LR Landa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Rapid hop diffusion of a G-protein-coupled receptor in the plasma membrane as revealed by single-molecule techniques
K Suzuki et al.
BIOPHYSICAL JOURNAL (2005)
β-arrestin binding to the β2-adrenergic receptor requires both receptor phosphorylation and receptor activation
C Krasel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Novel single chain cAMP sensors for receptor-induced signal propagation
VO Nikolaev et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Gi protein activation in intact cells involves subunit rearrangement rather than dissociation
M Bünemann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Measurement of the millisecond activation switch of G protein-coupled receptors in living cells
JP Vilardaga et al.
NATURE BIOTECHNOLOGY (2003)
cAMP and Ca2+ interplay:: a matter of oscillation patterns
M Zaccolo et al.
TRENDS IN NEUROSCIENCES (2003)
Targeting of cyclic AMP degradation to β2-adrenergic receptors by β-arrestins
SJ Perry et al.
SCIENCE (2002)
A β2 adrenergic receptor signaling complex assembled with the Ca2+ channel Cav1.2
MA Davare et al.
SCIENCE (2001)
Crystal structure of rhodopsin: A G protein-coupled receptor
K Palczewski et al.
SCIENCE (2000)