Journal
COMPUTERIZED MEDICAL IMAGING AND GRAPHICS
Volume 32, Issue 1, Pages 22-35Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.compmedimag.2007.08.012
Keywords
segmentation; deformable models; level sets; charged fluid model (CFM); Poisson's equation; electrostatic equilibrium; CT; MRI; 3DRA
Funding
- NATIONAL CENTER FOR RESEARCH RESOURCES [U54RR021813, P41RR013642] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF MENTAL HEALTH [R01MH071940] Funding Source: NIH RePORTER
- NCRR NIH HHS [P41 RR013642, P41 RR013642-05, U54 RR021813] Funding Source: Medline
- NIMH NIH HHS [R01 MH071940-01, R01 MH071940] Funding Source: Medline
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A new deformable model, the charged fluid model (CFM), that uses the simulation of charged elements was used to segment medical images. Poisson's equation was used to guide the evolution of the CFM in two steps. In the first step, the elements of the charged fluid were distributed along the propagating interface until electrostatic equilibrium was achieved. In the second step, the propagating front of the charged fluid was deformed in response to the image gradient. The CFM provided sub-pixel precision, required only one parameter setting, and required no prior knowledge of the anatomy of the segmented object. The characteristics of the CFM were compared to existing deformable models using CT and MR images. The results indicate that the CFM is a promising approach for the segmentation of anatomic structures in a wide variety of medical imaaes across different modalities. (c) 2007 Elsevier Ltd. All rights reserved.
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