Journal
COMPTES RENDUS MATHEMATIQUE
Volume 350, Issue 1-2, Pages 23-28Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.crma.2011.11.019
Keywords
-
Categories
Ask authors/readers for more resources
We present in this Note a new mathematical model designed to optimize and to rationalize the association between cytotoxic and antiangiogenic drugs in the treatment of a primary tumor. This model takes into account the non-linear intedinkings between both drugs. In particular, this original model integrates the influence of the vasculature state on the delivery of the drugs to the tumor. In the future, this model could be used in clinical oncology to optimize antiangiogenic-based combinational regimen so as to ensure a maximum efficacy. (C) 2011 Academie des sciences. Published by Elsevier Masson SAS. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available