Journal
COMPTES RENDUS CHIMIE
Volume 17, Issue 5, Pages 431-436Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.crci.2013.06.002
Keywords
Thiamine hydrochloride (VB1); 1,3-oxazines; Multicomponent reaction; Aqueous medium
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An efficient and convenient synthesis of 1,3-oxazine derivatives has been achieved by the one-pot, multicomponent condensation of alpha- or beta-naphthol, an aniline and formaldehyde using thiamine hydrochloride (VB1) as a versatile biodegradable and reusable catalyst in water as a universal solvent. (C) 2013 Published by Elsevier Masson SAS on behalf of Academie des sciences.
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