Journal
COMPTES RENDUS CHIMIE
Volume 16, Issue 12, Pages 1111-1117Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.crci.2013.06.006
Keywords
2-Amino-3-cyanopyridine; Multicomponent reaction; Aldehyde; Ketone; Malononitrile; Ammonium acetate; Solvent-free; TBBDA; PBBS
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Funding
- Bu-Ali Sina University, Center of Excellence in Development of Environmentally Friendly Methods for Chemical Synthesis (CEDEFMCS)
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A series of 2-amino-3-cyanopyridines were obtained from aryl aldehydes, substituted acetophenones, malononitrile and ammonium acetate in good to excellent yields by proceeding through a simple, mild and efficient procedure utilizing N,N,N ',N '-tetra-bromobenzene-1,3-disulfonamide [TBBDA and poly(N-bromo-N-ethylbenzene-1,3-disulfonamide) IPBBS] as catalysts. (C) 2013 Academie des sciences. Published by Elsevier Masson SAS. All rights reserved.
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