Journal
COMPTES RENDUS CHIMIE
Volume 16, Issue 3, Pages 239-243Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.crci.2012.11.007
Keywords
Copper free; Cross-coupling; Dipolar cycloaddition; 1,2,3-(NH)-triazoles; Silica supported; Aerobic condition; Zinc bromide
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An efficient one-pot cross-coupling/1,3-dipolar cycloaddition sequence was developed for a convenient synthesis of 4,5-disubstituted-1,2,3-(NH)-triazoles, starting from various acid chlorides, terminal alkynes and sodium azide in the presence of silica supported-zinc bromide under aerobic conditions. (C) 2012 Academie des sciences. Published by Elsevier Masson SAS. All rights reserved.
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