Journal
JOURNAL OF MEMBRANE SCIENCE
Volume 490, Issue -, Pages 139-151Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.memsci.2015.04.064
Keywords
Asymmetrical membranes; Wet and dry/wet techniques; Supercritical CO2; Electrospinning; Wound dressings
Categories
Funding
- Fundacao para a Ciencia e Tecnologia (FCT-Lisbon)
- COMPETE [UID/QUI/50006/2013, SFRH/BD/80648/2011]
- Fundação para a Ciência e a Tecnologia [SFRH/BD/80648/2011] Funding Source: FCT
Ask authors/readers for more resources
Healing a wound is a process that comprises sequential steps aimed to restore the structure and function of damaged cells and tissues. Since the antiquity, to promote an effective wound healing, different materials have been used to cover the wound. Nowadays, dressings that are able to mimic the structure and composition of skin are specifically designed to exhibit several required functions. To cope with this demand, different wound dressings have been produced using conventional techniques, during the last two decades. Among them, asymmetric ones present a dense top layer to protect the wound from physical damage and pathogen penetration and an inner porous layer that allows the exudates absorption, keeping the moisturized environment needed for effective skin regeneration. However, the production methods used so far, wet- and dry/wet-phase inversion techniques, present some limitations such as the use of toxic organic solvents, the lack of polymers variety and are very time-consuming. In addition, taking into account the worldwide economic status, sustainable procedures, like supercritical carbon dioxide (scCO(2)) - assisted phase inversion and electrospinning techniques can be adopted to produce suitable dressings for wound-management. Herein, a critical review of the methods used to produce asymmetric membranes is presented, highlighting the different properties that can be enhanced for wound healing purposes. (C) 2015 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available