Journal
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
Volume 12, Issue 6, Pages 544-553Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138620709788681961
Keywords
Biomaterials; cell adhesion; cell-material interactions; combinatorial screening; gradient; hydrogel; microarray; polymer; tissue engineering
Funding
- National Academy of Science post-doctoral fellowship programs
- NIST-NSF Summer Undergraduate Research Fellowship
- NIST
- NIH/NIBIB [R21-EB006497-01]
- RESBIO NIH [P41-EB001046]
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Gradients and arrays have become very useful to the fields of tissue engineering and biomaterials. Both gradients and arrays make efficient platforms for screening cell response to biomaterials. Graded biomaterials also have functional applications and make useful substrates for fundamental studies of cell phenomena such as migration. This article will review the use of gradients and arrays in tissue engineering and biomaterials research, with a focus on cellular and biologic responses.
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