Journal
COLORECTAL DISEASE
Volume 14, Issue 9, Pages e521-e529Publisher
WILEY
DOI: 10.1111/j.1463-1318.2012.03103.x
Keywords
Inferior mesenteric artery; colectomy; sigmoidectomy; diverticulitis; diverticular disease; laparoscopy; anastomotic leakage
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Aim A meta-analysis was conducted to compare preservation with ligation of the inferior mesenteric artery (IMA) during sigmoidectomy for diverticular disease. Method Randomized and non-randomized clinical trials were identified using the following electronic databases: Medline, Embase, Cochrane Central Register of Controlled Trials, CINAHL, BioMed Central, Science Citation Index, Greynet, SIGLE, National Technological Information Service, British Library Integrated Catalogue. The analysed end-points were the anastomotic leakage rate, overall morbidity and 30-day postoperative mortality. Results Four studies were included involving 400 patients. The anastomotic leakage rate was 7.3% in the preservation group and 11.3% in the ligation group. There was no statistically significant difference between the groups (OR 0.72, 95% CI 0.114.76; P = 0.73). Overall morbidity and 30-day postoperative mortality were not compared since these data were reported in only one study. Conclusion The meta-analysis did not show any advantage for preservation of the IMA during sigmoid colectomy for diverticular disease in terms of anastomotic leakage.
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