Journal
COLLOIDS AND SURFACES B-BIOINTERFACES
Volume 119, Issue -, Pages 162-165Publisher
ELSEVIER
DOI: 10.1016/j.colsurfb.2014.04.018
Keywords
Cellulose nanocrystal; Toxicity; Cancer cell
Funding
- National Research Foundation of Korea (NRF) - Ministry of Future Creation and Science [2013R1A1A1058670, 2013R1A1A2016781]
- Korea Health Technology R&D Project of the Ministry of Health and Welfare of the Republic of Korea [A110552]
- Korea Health Promotion Institute [A110552] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
- National Research Foundation of Korea [2013R1A1A2016781, 2013R1A1A1058670] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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A controlled preparation of cellulose nanocrystals of different sizes and shapes has been carried out by acid hydrolysis of microcrystalline cellulose. The size- and concentration-dependent toxicity effects of the resulting cellulose nanocrystals were evaluated against two different cell lines, NIH3T3 murine embryo fibroblasts and HCT116 colon adenocarcinoma. It could serve as a therapeutic platform for cancer treatment. (C) 2014 Elsevier B.V. All rights reserved.
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